View a few of our most notable publications from 2018 – 2019:

ASSC Publications

 

When to apply sunscreen: a consensus statement for Australia and New Zealand

Whiteman, David C., Neale, Rachel E., Aitken, Joanne, Gordon, Louisa, Green, Adele C., Janda, Monika, Olsen, Catherine M., Soyer, H. Peter and Sunscreen Summit Policy Group (2019) When to apply sunscreen: a consensus statement for Australia and New Zealand. Australian and New Zealand Journal of Public Health, doi:10.1111/1753-6405.12873

Increase in preventive behaviour by organ transplant recipients after sun protection information in a skin cancer surveillance clinic

Papier, K., Gordon, L.G., Khosrotehrani, K., Isbel, N., Campbell, S., Griffin, A. and Green, A.C. (2018) Increase in preventive behaviour by organ transplant recipients after sun protection information in a skin cancer surveillance clinic. British Journal of Dermatology179 5: 1195-1196. doi:10.1111/bjd.16836

Management of organ transplant recipients attending a high-throughput skin cancer surgery and surveillance clinic in Queensland

Papier K, Gordon LG, Khosrotehrani K, Isbel N, Campbell S, Griffin A, Green AC. Management of organ transplant recipients attending a high-throughput skin cancer surgery and surveillance clinic in Queensland. Br J Dermatol. 2018 [Epub ahead of print]

The effects of a multidisciplinary high-throughput skin clinic on healthcare costs of organ transplant recipients

Gordon LG, Rodriguez A, Papier K, Khosrotehrani K, Isbel N , Campbell S, Griffin A , Green AC. The effects of a multidisciplinary high-throughput skin clinic on healthcare costs of organ transplant recipients. J Euro Acad Derm Venerol. 2019 Feb 1. doi: 10.1111/jdv.15458.

ASSC Member Publications

 

Cohort studies on melanoma and keratinocyte skin cancer: a systematic review

Olsen CM, Neale RE, Whiteman DC. (2019) Cohort studies on melanoma and keratinocyte skin cancer: a systematic review (open source)

Optimising intratumoral treatment of head and neck squamous cell carcinoma models with the diterpene ester Tigilanol tiglate

Barnett, Catherine M. E., Broit, Natasa, Yap, Pei-Yi, Cullen, Jason K., Parsons, Peter G., Panizza, Benedict J. and Boyle, Glen M (2018) Optimising intratumoral treatment of head and neck squamous cell carcinoma models with the diterpene ester Tigilanol tiglate. Investigational New Drugs, 1-8. doi:10.1007/s10637-018-0604-y

Clinically-relevant rapamycin treatment regimens enhance CD8+ effector memory T cell function in the skin and allow their infiltration into cutaneous squamous cell carcinoma

Jung, Ji-Won, Veitch, Margaret, Bridge, Jennifer A., Overgaard, Nana H., Cruz, Jazmina L., Linedale, Richard, Franklin, Michael E., Saunders, Nicholas A., Simpson, Fiona, Frazer, Ian H., Steptoe, Raymond J. and Wells, James W. (2018) Clinically-relevant rapamycin treatment regimens enhance CD8+ effector memory T cell function in the skin and allow their infiltration into cutaneous squamous cell carcinoma. OncoImmunology7 9: 1-16. doi:10.1080/2162402X.2018.1479627

Targeting the XPO1-dependent nuclear export of E2F7 reverses anthracycline resistance in head and neck squamous cell carcinomas

Saenz-Ponce, Natalia, Pillay, Rachael, de Long, Lilia Merida, Kashyap, Trinayan, Argueta, Christian, Landesman, Yosef, Hazar-Rethinam, Mehlika, Boros, Samuel, Panizza, Benedict, Jacquemyn, Maarten, Daelemans, Dirk, Gannon, Orla M. and Saunders, Nicholas A. (2018) Targeting the XPO1-dependent nuclear export of E2F7 reverses anthracycline resistance in head and neck squamous cell carcinomas. Science Translational Medicine10 447: eaar7223. doi:10.1126/scitranslmed.aar7223

An ex vivo human tumour assay reveals distinct patterns of EGFR trafficking in squamous cell carcinoma correlating to therapeutic outcomes

Joseph, Shannon R., Gaffney, Daniel, Barry, Rachael, Hu, Lingbo, Banushi, Blerida, Wells, James W., Lambie, Duncan, Strutton, Geoff, Porceddu, Sandro V., Burmeister, Bryan, Leggatt, Graham R., Schaider, Helmut, Dolcetti, Riccardo, Frazer, Ian H., Saunders, Nicholas A., Foote, Matthew, Soyer, H. Peter and Simpson, Fiona (2018) An ex vivo human tumour assay reveals distinct patterns of EGFR trafficking in squamous cell carcinoma correlating to therapeutic outcomes. Journal of Investigative Dermatology, . doi:10.1016/j.jid.2018.06.190

OM, Antonsson A, Bennett I and Saunders NA. Viral infections and breast cancer – a current perspective”. Cancer Letters.  420:182-189, 2018.

Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways

Duffy, David L., Zhu, Gu, Li, Xin, Sanna, Marianna, Iles, Mark M., Jacobs, Leonie C., Evans, David M., Yazar, Seyhan, Beesley, Jonathan, Law, Matthew H., Kraft, Peter, Visconti, Alessia, Taylor, John C., Lui, Fan, Wright, Margaret J., Henders, Anjali K., Bowdler, Lisa, Glass, Dan, Ikram, Arfan M., Uitterlinden, André G., Madden, Pamela A., Heath, Andrew C., Nelson, Elliot C., Green, Adele C., Chanock, Stephen, Barrett, Jennifer H., Brown, Matthew A., Hayward, Nicholas K., MacGregor, Stuart, Sturm, Richard A., Hewitt, Alex W., Melanoma GWAS Consortium, Kayser, Manfred, Hunter, David J., Newton Bishop, Julia A., Spector, Timothy D., Montgomery, Grant W., Mackey, David A., Smith, George Davey, Nijsten, Tamar E., Bishop, D. Timothy, Bataille, Veronique, Falchi, Mario, Han, Jiali and Martin, Nicholas G. (2018) Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways.Nature Communications9 1: . doi:10.1038/s41467-018-06649-5

RGS7 is recurrently mutated in melanoma and promotes migration and invasion of human cancer cells

Qutob N, Masuho I, Alon M, Emmanuel R, Cohen I, Di Pizio A, Madore J, Elkahloun A, Ziv T, Levy R, Gartner JJ, Hill VK, Lin JC, Hevroni Y, Greenberg P, Brodezki A, Rosenberg SA, Kosloff M, Hayward NK, Admon A, Niv MY, Scolyer RA, Martemyanov KA, Samuels Y. RGS7 is recurrently mutated in melanoma and promotes migration and invasion of human cancer cells. Sci Rep. 2018 Jan 12;8(1):653.

The protective role of DOT1L in UV-induced melanomagenesis

Zhu B, Chen S, Wang H, Yin C, Han C, Peng C, Liu Z, Wan L, Zhang X, Zhang J, Lian CG, Ma P, Xu ZX, Prince S, Wang T, Gao X, Shi Y, Liu D, Liu M, Wei W, Wei Z, Pan J, Wang Y, Xuan Z, Hess J, Hayward NK, Goding CR, Chen X, Zhou J, Cui R. The protective role of DOT1L in UV-induced melanomagenesis. Nat Commun. 2018 Jan 17;9(1):259.

Germline mutations in candidate predisposition genes in individuals with cutaneous melanoma and at least two independent additional primary cancers

Pritchard AL, Johansson PA, Nathan V, Howlie M, Symmons J, Palmer JM, Hayward NK. Germline mutations in candidate predisposition genes in individuals with cutaneous melanoma and at least two independent additional primary cancers. PLoS One. 2018 Apr 11;13(4):e0194098.

Telomere sequence content can be used to determine ALT activity in tumours

Lee M, Teber ET, Holmes O, Nones K, Patch AM, Dagg RA, Lau LMS, Lee JH, Napier CE, Arthur JW, Grimmond SM, Hayward NK, Johansson PA, Mann GJ, Scolyer RA, Wilmott JS, Reddel RR, Pearson JV, Waddell N, Pickett HA. Telomere sequence content can be used to determine ALT activity in tumours. Nucleic Acids Res. 2018 Jun 1;46(10):4903-4918.

Proteomic phenotyping of metastatic melanoma reveals putative signatures of MEK inhibitor response and prognosis

Krisp C, Parker R, Pascovici D, Hayward NK, Wilmott JS, Thompson JF, Mann GJ, Long GV, Scolyer RA, Molloy MP. Proteomic phenotyping of metastatic melanoma reveals putative signatures of MEK inhibitor response and prognosis. Br J Cancer. 2018 Sep;119(6):713-723.

Somatic inactivating PTPRJ mutations and dysregulated pathways identified in canine malignant melanoma by integrated comparative genomic analysis

Hendricks WPD, Zismann V, Sivaprakasam K, Legendre C, Poorman K, Tembe W, Perdigones N, Kiefer J, Liang W, DeLuca V, Stark M, Ruhe A, Froman R, Duesbery NS, Washington M, Aldrich J, Neff MW, Huentelman MJ, HAYWARD N, Brown K, Thamm D, Post G, Khanna C, Davis B, Breen M, Sekulic A, Trent JM. Somatic inactivating PTPRJ mutations and dysregulated pathways identified in canine malignant melanoma by integrated comparative genomic analysis. PLoS Genet. 2018 Sep 6;14(9):e1007589.

Comprehensive Study of the Clinical Phenotype of Germline BAP1 Variant-Carrying Families Worldwide

Walpole S, Pritchard AL, Cebulla CM, Pilarski R, Stautberg M, Davidorf FH, de la Fouchardière A, Cabaret O, Golmard L, Stoppa-Lyonnet D, Garfield E, Njauw CN, Cheung M, Turunen JA, Repo P, Järvinen RS, van Doorn R, Jager MJ, Luyten GPM, Marinkovic M, Chau C, Potrony M, Höiom V, Helgadottir H, Pastorino L, Bruno W, Andreotti V, Dalmasso B, Ciccarese G, Queirolo P, Mastracci L, Wadt K, Kiilgaard JF, Speicher MR, van Poppelen N, Kilic E, Al-Jamal RT, Dianzani I, Betti M, Bergmann C, Santagata S, Dahiya S, Taibjee S, Burke J, Poplawski N, O’Shea SJ, Newton-Bishop J, Adlard J, Adams DJ, Lane AM, Kim I, Klebe S, Racher H, Harbour JW, Nickerson ML, Murali R, Palmer JM, Howlie M, Symmons J, Hamilton H, Warrier S, Glasson W, Johansson P, Robles-Espinoza CD, Ossio R, de Klein A, Puig S, Ghiorzo P, Nielsen M, Kivelä TT, Tsao H, Testa JR, Gerami P, Stern MH, Paillerets BB, Abdel-Rahman MH, Hayward NK. (2018) Comprehensive Study of the Clinical Phenotype of Germline BAP1 Variant-Carrying Families Worldwide. J Natl Cancer Inst. 2018 Dec 1;110(12):1328-1341.

Acetylsalicylic acid governs the effect of sorafenib in RAS- mutant cancers

Hammerlindl, Heinz, Ravindran Menon, Dinoop, Hammerlindl, Sabrina, Emran, Abdullah Al, Torrano, Joachim, Sproesser, Katrin, Thakkar, Divya, Xiao, Min, Atkinson, Victoria G., Gabrielli, Brian, Haass, Nikolas K., Herlyn, Meenhard, Krepler, Clemens and Schaider, Helmut (2018) Acetylsalicylic acid governs the effect of sorafenib in RAS- mutant cancers. Clinical Cancer Research, 24 5: 1090-1102. doi:10.1158/1078-0432.CCR-16-2118

Distinct histone modifications denote early stress-induced drug tolerance in cancer

Emran, Abdullah Al, Marzese, Diego M., Menon, Dinoop Ravindran, Stark, Mitchell S., Torrano, Joachim, Hammerlindl, Heinz, Zhang, Gao, Brafford, Patricia, Salomon, Matthew P., Nelson, Nellie, Hammerlindl, Sabrina, Gupta, Deepesh, Mills, Gordon B., Lu, Yiling, Sturm, Richard A., Flaherty, Keith, Hoon, Dave S. B., Gabrielli, Brian, Herlyn, Meenhard and Schaider, Helmut (2017) Distinct histone modifications denote early stress-induced drug tolerance in cancer. Oncotarget, 9 9: 8206-8222. doi:10.18632/oncotarget.23654

Tumor cell-intrinsic phenotypic plasticity facilitates adaptive cellular reprogramming driving acquired drug resistance

Hammerlindl, Heinz and Schaider, Helmut (2017) Tumor cell-intrinsic phenotypic plasticity facilitates adaptive cellular reprogramming driving acquired drug resistance. Journal of Cell Communication and Signaling, 12 1: 133-141. doi:10.1007/s12079-017-0435-1

When to apply sunscreen: a consensus statement for Australia and New Zealand

Whiteman, David C., Neale, Rachel E., Aitken, Joanne, Gordon, Louisa, Green, Adele C., Janda, Monika, Olsen, Catherine M., Soyer, H. Peter and Sunscreen Summit Policy Group (2019) When to apply sunscreen: a consensus statement for Australia and New Zealand. Australian and New Zealand Journal of Public Health, doi:10.1111/1753-6405.12873

Trends in Melanoma Incidence Rates in Eight Susceptible Populations through 2015

Olsen CM, Green AC, Pandeya N, Whiteman DC. (2018) Trends in Melanoma Incidence Rates in Eight Susceptible Populations through 2015. J Invest Dermatol. 2018 Dec 19. pii: S0022-202X(18)30008-3. doi: 10.1016/j.jid.2018.12.006

Association between Phenotypic Characteristics and Melanoma in a Large Prospective Cohort Study

Olsen CM, Pandeya N, Thompson BS, Dusingize JC, Green AC, Neale RE, Whiteman DC; QSkin Study. (2018) Association between Phenotypic Characteristics and Melanoma in a Large Prospective Cohort Study. J Invest Dermatol. 2018 Oct 24. pii: S0022-202X(18)32692-7. doi: 10.1016/j.jid.2018.09.022

Smoking and Cutaneous Melanoma: Findings from the QSkin Sun and Health Cohort Study

Dusingize JC, Olsen CM, Pandeya N, Thompson BS, Webb PM, Green AC, Neale RE, Whiteman DC; QSkin Study. Smoking and Cutaneous Melanoma: Findings from the QSkin Sun and Health Cohort Study. Cancer Epidemiol Biomarkers Prev. 2018 Aug;27(8):874-881. doi: 10.1158/1055-9965.EPI-17-1056.

Risk Stratification for Melanoma: Models Derived and Validated in a Purpose-Designed Prospective Cohort

Olsen CM, Pandeya N, Thompson BS, Dusingize JC, Webb PM, Green AC, Neale RE, Whiteman DC; QSkin Study. Risk Stratification for Melanoma: Models Derived and Validated in a Purpose-Designed Prospective Cohort. J Natl Cancer Inst. 2018 Oct 1;110(10):1075-1083. doi: 10.1093/jnci/djy023

How many melanomas might be prevented if more people applied sunscreen regularly?

Olsen CM, Wilson LF, Green AC, Biswas N, Loyalka J, Whiteman DC. How many melanomas might be prevented if more people applied sunscreen regularly?  Br J Dermatol. 2018 Jan;178(1):140-147. doi: 10.1111/bjd.16079. Epub 2017 Dec 14

Genetic variation in IRF4 expression modulates growth characteristics, tyrosinase expression and interferon-gamma response in melanocytic cells

Chhabra, Yash, Yong, Hilary X. L., Fane, Mitchell E., Soogrim, Arish, Lim, Wen, Mahiuddin, Dayana Nur, Kim, Reuben S. Q., Ashcroft, Melinda, Beatson, Scott A., Ainger, Stephen A., Smit, Darren J., Jagirdar, Kasturee, Walker, Graeme J., Sturm, Richard A. and Smith, Aaron G. (2018) Genetic variation in IRF4 expression modulates growth characteristics, tyrosinase expression and interferon-gamma response in melanocytic cells. Pigment Cell & Melanoma Research31 1: 51-63. doi:10.1111/pcmr.12620

Iris pigmented lesions as a marker of cutaneous melanoma risk: an Australian case-control study

Laino, A. M., Berry, E. G., Jagirdar, K., Lee, K. J., Duffy, D. L., Soyer, H. P. and Sturm, R. A. (2018) Iris pigmented lesions as a marker of cutaneous melanoma risk: an Australian case-control study. British Journal of Dermatology,178 5: 1119-1127. doi:10.1111/bjd.16323

Whole-exome sequencing of acquired nevi identifies mechanisms for development and maintenance of benign neoplasms

Stark, Mitchell S., Tan, Jean-Marie, Tom, Lisa, Jagirdar, Kasturee, Lambie, Duncan, Schaider, Helmut, Soyer, H. Peter and Sturm, Richard A. (2018) Whole-exome sequencing of acquired nevi identifies mechanisms for development and maintenance of benign neoplasms (vol 138, pg 1636, 2018). Journal of Investigative Dermatology138 9: 2085-2085. doi:10.1016/j.jid.2018.06.174

Towards the full spectrum of genes for human skin colour

Sturm, Richard A. and Duffy, David L. (2018) Towards the full spectrum of genes for human skin colour. Pigment Cell and Melanoma Research31 4: 457-458. doi:10.1111/pcmr.12691

J.E. Rayner, E.K. McMeniman, D.L. Duffy, B. De’Ambrosis, B.M. Smithers, K. Jagirdar, K.J. Lee, H.P. Soyer, R.A. Sturm.  Phenotypic and Genotypic Analysis of Amelanotic and Hypomelanotic Melanoma Patients. Journal of the European Academy of Dermatology and Venerology (JEADV), in press (2019). Epub  Jan 24.

Postoperative Concurrent Chemoradiotherapy Versus Postoperative Radiotherapy in High-Risk Cutaneous Squamous Cell Carcinoma of the Head and Neck: The Randomized Phase III TROG 05.01 Trial

Porceddu, Sandro Virgilio, Bressel, Mathias, Poulsen, Michael Geoffrey, Stoneley, Adam, Veness, Michael John, Kenny, Lizbeth Moira, Wratten, Chris, Corry, June, Cooper, Stephen, Fogarty, Gerald Blaise, Collins, Marnie, Collins, Michael Kevin, Macann, Andrew Martin John, Milross, Christopher Gerard, Penniment, Michael Gordon, Liu, Howard Yu-Hao, King, Madeleine Trudy, Panizza, Benedict James and Rischin, Danny. (2018) Postoperative Concurrent Chemoradiotherapy Versus Postoperative Radiotherapy in High-Risk Cutaneous Squamous Cell Carcinoma of the Head and Neck: The Randomized Phase III TROG 05.01 Trial. Journal of Clinical Oncology, 36 13: 1275-1283. 2018

Head and neck squamous cell carcinoma of unknown primary: Outcomes of a pre-defined institutional treatment policy in a region with a high prevalence of skin cancer

Huo, Michael, Panizza, Benedict, Bernard, Anne and Porceddu, Sandro V. (2018) Head and neck squamous cell carcinoma of unknown primary: Outcomes of a pre-defined institutional treatment policy in a region with a high prevalence of skin cancer. Oral Oncology, 77 43-48. 2018

Large-giant congenital melanocytic nevi: moving beyond NRAS mutations

Stark MS (2019). Large-giant congenital melanocytic nevi: moving beyond NRAS mutations. J Invest Dermatol. doi:10.1016/j.jid.2018.10.003

Defining the molecular genetics of dermoscopic naevus patterns

Tan, Jean-Marie, Tom, Lisa N., Soyer, H. Peter and Stark, Mitchell S. (2018) Defining the molecular genetics of dermoscopic naevus patterns. Dermatology , 1-16. doi:10.1159/000493892

The BRAF and NRAS mutation prevalence in dermoscopic subtypes of acquired naevi reveals constitutive MAPK pathway activation

Tan, J. M., Tom, L. N., Jagirdar, K., Lambie, D., Schaider, H., Sturm, R. A., Soyer, H. P. and Stark, M. S. (2018) The BRAF and NRAS mutation prevalence in dermoscopic subtypes of acquired naevi reveals constitutive MAPK pathway activation. British Journal of Dermatology178 1: 191-197. doi:10.1111/bjd.15809

Magnolol induces cell death through PI3K/Akt mediated epigenetic modifications boosting treatment of BRAF- and NRAS-mutant melanoma

Emran AA, Chinna Chowdary BR, Ahmed F, Hammerlindl H, Huefner A, Haass NK, Schuehly W, Schaider H (2019) Magnolol induces cell death through PI3K/Akt mediated epigenetic modifications boosting treatment of BRAF- and NRAS-mutant melanoma. Cancer Med, accepted 23rd December 2018, PMID: TBA; doi: 10.1002/cam4.1978

 

RAB27A promotes melanoma cell invasion and metastasis via regulation of pro-invasive exosomes.

Guo D, Lui GYL, Lai SL, Wilmott JS, Tikoo S, Jackett LA, Quek C, Brown DL, Sharp DM, Kwan RYQ, Chacon D, Wong JH, Beck D, van Geldermalsen M, Holst J, Thompson JF, Mann GJ, Scolyer RA, Stow JL, Weninger W, Haass NK, Beaumont KA (2019) RAB27A promotes melanoma cell invasion and metastasis via regulation of pro-invasive exosomes. Int J Cancer, 2018 Dec 17 [Epub ahead of print] PMID: 30556600; doi: 10.1002/ijc.32064

Stochastic models of cell invasion with fluorescent cell cycle indicators

Simpson MJ, Jin W, Vittadello ST, Tambyah T, Ryan J, Gunasingh G, Haass NK, McCue SW (2018) Stochastic models of cell invasion with fluorescent cell cycle indicators. Physica A 510: 375-386, PMID: n/a; doi: 10.1016/j.physa.2018.06.128

The Role of Melanoma Cell-Stroma Interaction in Cell Motility, Invasion, and Metastasis.

Ju RJ, Stehbens SJ, Haass NK(2018) The Role of Melanoma Cell-Stroma Interaction in Cell Motility, Invasion, and Metastasis. Research Topic: “Insights into Biomarkers, Cytokines, and Chemokines in Skin Cancer” Front Med (Lausanne) 5: 307; PMID: 30460237; doi: 10.3389/fmed.2018.00307

FGFR2-activating mutations disrupt cell polarity to potentiate migration and invasion in endometrial cancer cell models.

Stehbens SJ, Ju RJ, Adams MN, Perry S, Haass NK, Bryant DM, Pollock PM (2018). FGFR2-activating mutations disrupt cell polarity to potentiate migration and invasion in endometrial cancer cell models. J Cell Sci 131: jcs213678; PMID: 30002137; doi: 10.1242/jcs.213678

Endogenous Replication Stress Marks Melanomas Sensitive to CHEK1 Inhibitors In Vivo

Oo ZY, Stevenson AJ, Proctor MA, Daignault SM, Walpole S, Lanagan C, Chen MS, Škalamera D, Spoerri L, Ainger S, Sturm RA, Haass NK, Gabrielli B (2018) Endogenous Replication Stress Marks Melanomas Sensitive to CHEK1 Inhibitors In Vivo. Clin Cancer Res 24: 2901-2912; PMID: 29535131; doi: 10.1158/1078-0432.CCR-17-2701

Microenvironment-Driven Dynamic Heterogeneity and Phenotypic Plasticity as a Mechanism of Melanoma Therapy Resistance

Ahmed F, Haass NK (2018), Microenvironment-Driven Dynamic Heterogeneity and Phenotypic Plasticity as a Mechanism of Melanoma Therapy Resistance. Front Oncol 8: 173; PMID: 29881716; doi: 10.3389/fonc.2018.00173

HDAC inhibitors restore BRAF-inhibitor sensitivity by altering PI3K and survival signalling in a subset of melanoma.

Gallagher SJ, Gunatilake D, Beaumont KA, Sharp DM, Tiffen JC, Heinemann A, Weninger W, Haass NK, Wilmott JS, Madore J, Ferguson PM, Rizos H, Hersey P (2018) HDAC inhibitors restore BRAF-inhibitor sensitivity by altering PI3K and survival signalling in a subset of melanoma.Int J Cancer 142: 1926-1937; PMID: 29210065; doi: 10.1002/ijc.31199

Mathematical Models for Cell Migration with Real-Time Cell Cycle Dynamics.

Vittadello ST, McCue SW, Gunasingh G, Haass NK*, Simpson MJ* (2018) Mathematical Models for Cell Migration with Real-Time Cell Cycle Dynamics. Biophys J 114: 1241-1253; PMID: 29539409; doi: 10.1016/j.bpj.2017.12.041

Clustering of prevention behaviours in patients with high-risk primary melanoma

Green AC Hughes MCB, von Schuckmann LA, Khosrotehrani K, Smithers BM. Clustering of prevention behaviours in patients with high-risk primary melanoma. Psychooncol 2018; 27: 1442-1449.

High prevalence of skin cancers and actinic keratoses in lung transplant recipients

Sahebian A, Pandeya N, Chambers DC, Soyer HP, Green AC. High prevalence of skin cancers and actinic keratoses in lung transplant recipients. J Heart Lung Transplant 2018; 37:420-22.

Nodular melanoma: a histopathologic entity?

Green AC, Viros A, Hughes MCB, Gaudy-Marqueste C, Akhras V, Cook MG, Marais R. Nodular melanoma: a histopathologic entity? Acta Derm-Venereol 2018; 98: 460-462.

Survival of patients with early invasive melanoma down-staged under the new 8th AJCC edition

von Schuckmann LA, Hughes MB, Lee R, Lorigan P, Khosrotehrani K, Smithers BM, Green AC. Survival of patients with early invasive melanoma down-staged under the new 8th AJCC edition.  JAAD 2019; 80: 272-274.

Management of organ transplant recipients attending a high-throughput skin cancer surgery and surveillance clinic in Queensland

Papier K, Gordon LG, Khosrotehrani K, Isbel N, Campbell S, Griffin A, Green AC. Management of organ transplant recipients attending a high-throughput skin cancer surgery and surveillance clinic in Queensland. Br J Dermatol. 2018 [Epub ahead of print]

Increase in preventive behaviour by organ transplant recipients after sun protection information in a skin cancer surveillance clinic

Papier, K., Gordon, L.G., Khosrotehrani, K., Isbel, N., Campbell, S., Griffin, A. and Green, A.C. (2018) Increase in preventive behaviour by organ transplant recipients after sun protection information in a skin cancer surveillance clinic. British Journal of Dermatology179 5: 1195-1196. doi:10.1111/bjd.16836

Sun Protection Among Organ Transplant Recipients After Participation in a Skin Cancer Research Study

Hartman RI, Green AC, Gordon LG (2018) Sun Protection Among Organ Transplant Recipients After Participation in a Skin Cancer Research Study. Skin Tumours and Allograft Recipients (STAR) Study. JAMA Dermatol. 2018 Jul 1;154(7):842-844. doi: 10.1001/jamadermatol.2018.1164. PMID: 29874380

The effects of a multidisciplinary high-throughput skin clinic on healthcare costs of organ transplant recipients

Gordon LG, Rodriguez A, Papier K, Khosrotehrani K, Isbel N , Campbell S, Griffin A , Green AC. The effects of a multidisciplinary high-throughput skin clinic on healthcare costs of organ transplant recipients. J Euro Acad Derm Venerol. 2019 Feb 1. doi: 10.1111/jdv.15458.

A natural history of actinic keratosis and cutaneous squamous cell carcinoma microbiomes

Wood, David L. A., Lachner, Nancy, Tan, Jean-Marie, Tang, Stephanie, Angel, Nicola, Laino, Antonia, Linedale, Richard, Lê Cao, Kim-Anh, Morrison, Mark, Frazer, Ian H., Soyer, H. Peter and Hugenholtz, Philip (2018) A natural history of actinic keratosis and cutaneous squamous cell carcinoma microbiomes. MBio9 5: . doi:10.1128/mBio.01432-18

An ex vivo human tumour assay reveals distinct patterns of EGFR trafficking in squamous cell carcinoma correlating to therapeutic outcomes

Joseph, Shannon R., Gaffney, Daniel, Barry, Rachael, Hu, Lingbo, Banushi, Blerida, Wells, James W., Lambie, Duncan, Strutton, Geoff, Porceddu, Sandro V., Burmeister, Bryan, Leggatt, Graham R., Schaider, Helmut, Dolcetti, Riccardo, Frazer, Ian H., Saunders, Nicholas A., Foote, Matthew, Soyer, H. Peter and Simpson, Fiona (2018) An ex vivo human tumour assay reveals distinct patterns of EGFR trafficking in squamous cell carcinoma correlating to therapeutic outcomes. Journal of Investigative Dermatology, . doi:10.1016/j.jid.2018.06.190

Clinically-relevant rapamycin treatment regimens enhance CD8+ effector memory T cell function in the skin and allow their infiltration into cutaneous squamous cell carcinoma

Jung, Ji-Won, Veitch, Margaret, Bridge, Jennifer A., Overgaard, Nana H., Cruz, Jazmina L., Linedale, Richard, Franklin, Michael E., Saunders, Nicholas A., Simpson, Fiona, Frazer, Ian H., Steptoe, Raymond J. and Wells, James W. (2018) Clinically-relevant rapamycin treatment regimens enhance CD8+ effector memory T cell function in the skin and allow their infiltration into cutaneous squamous cell carcinoma. OncoImmunology7 9: 1-16. doi:10.1080/2162402X.2018.1479627

Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways.

Duffy DL, Zhu G, Li X, Sanna M, Iles MM, Jacobs LC, Evans DM, Yazar S, Beesley J, Law MH, Kraft P, Visconti A, Taylor JC, Liu F, Wright MJ, Henders AK, Bowdler L, Glass D, Ikram MA, Uitterlinden AG, Madden PA, Heath AC, Nelson EC, Green AC, Chanock S, Barrett JH, Brown MA, Hayward NK, MacGregor S, Sturm RA, Hewitt AW; Melanoma GWAS Consortium, Kayser M, Hunter DJ, Newton Bishop JA, Spector TD, Montgomery GW, Mackey DA, Smith GD, Nijsten TE, Bishop DT, Bataille V, Falchi M, Han J, Martin NG. Nat Commun. 2018 Nov 14;9(1):4774. doi: 10.1038/s41467-018-06649-5. Erratum in: Nat Commun. 2019 Jan 14;10(1):299.

 

Cell-type-specific eQTL of primary melanocytes facilitates identification of melanoma susceptibility genes.

Zhang T, Choi J, Kovacs MA, Shi J, Xu M; NISC Comparative Sequencing Program; Melanoma Meta-Analysis Consortium, Goldstein AM, Trower AJ, Bishop DT, Iles MM, Duffy DL, MacGregor S, Amundadottir LT, Law MH, Loftus SK, Pavan WJ, Brown KM. Genome Res. 2018 Nov;28(11):1621-1635. doi: 10.1101/gr.233304.117. Epub 2018 Oct 17.

 

Combining common genetic variants and non-genetic risk factors to predict risk of cutaneous melanoma.

Gu F, Chen TH, Pfeiffer RM, Fargnoli MC, Calista D, Ghiorzo P, Peris K, Puig S, Menin C, De Nicolo A, Rodolfo M, Pellegrini C, Pastorino L, Evangelou E, Zhang T, Hua X, DellaValle CT, Timothy Bishop D, MacGregor S, Iles MI, Law MH, Cust A, Brown KM, Stratigos AJ, Nagore E, Chanock S, Shi J, Consortium MM, Consortium M, Landi MT. Hum Mol Genet. 2018 Dec 1;27(23):4145-4156. doi: 10.1093/hmg/ddy282.

 

Assessing the Incremental Contribution of Common Genomic Variants to Melanoma Risk Prediction in Two Population-Based Studies.

Cust AE, Drummond M, Kanetsky PA; Australian Melanoma Family Study Investigators; Leeds Case-Control Study Investigators, Goldstein AM, Barrett JH, MacGregor S, Law MH, Iles MM, Bui M, Hopper JL, Brossard M, Demenais F, Taylor JC, Hoggart C, Brown KM, Landi MT, Newton-Bishop JA, Mann GJ, Bishop DT. J Invest Dermatol. 2018 Dec;138(12):2617-2624. doi: 10.1016/j.jid.2018.05.023. Epub 2018 Jun 8.

Polyunsaturated fatty acids and risk of melanoma: A Mendelian randomisation analysis.

Liyanage UE, Law MH, Ong JS, Cust AE, Mann GJ, Ward SV; Melanoma Meta-Analysis Consortium, Gharahkhani P, Iles MM, MacGregor S. Int J Cancer. 2018 Aug 1;143(3):508-514. doi: 10.1002/ijc.31334. Epub 2018 Mar 5.